Trainees' Symposium April 2006
Edinburgh
Breast Cases
Diagnosis: Invasive lobular carcinoma - pleomorphic variant
- Features:
- Infiltrating malignant cells with a separated 'lobular' pattern
- Abundant eosinophilic 'myoid' cytoplasm
- Grade 3 nuclei
- E cadherin negative
- ER staining tends to be less strongly positive
