Trainees' Symposium April 2006
Edinburgh
Breast Cases

Slide 6 Images, diagnosis & features

Diagnosis: Low grade adenosquamous carcinoma


• Features:


• Infiltrating malignant glands with focal squamous differentiation
• Characteristic 'fibromatosis-like' stromal reaction
• CK 5/6 & P63 positive basal layer surrounding infiltrating tumour nests
• Excellent prognosis if 'pure'