Adenomyoepithelioma
Adenomyoepithelioma - Left - macro photo showing intracystic 2.0 cm nodule
Right - low power merged photo (original mag x 1.25)
Adenomyoepithelioma - low power view of intracystic component
Adenomyoepithelioma - distinct luminal epithelial acini separated by abundant myoepithelial cells.
See next image for detail
Luminal epithelial (A) and myoepithelial (B) elements in an adenomyoepithelioma. 'Mouse over' for labels.
Arrow points to a luminal epithelial cell mitosis.
Luminal epithelial component marked by CK 7 staining (left) and myoepithelial elements marked by CK 5/6 staining (right).
Myoepithelial elements showing spindle cell metaplasia and mitotic activity. The presence of mitotic figures and an infiltrative growth pattern have been assosciated with malignant potential in these tumours
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Papillomas - adenomyoepithelioma