HOME PAGE PRACTICE & PROTOCOLS INVESTIGATIONS BENIGN / BORDERLINE MALIGNANT CASE MATERIAL

Malignant microcalcification (1)





See also general practice points, malignant microcalcification (2) and benign microcalcification parts 1 & 2



DCIS






Mammogram - cluster of microcalcs (red arrow) typical of high grade comedo DCIS - Courtesy of Jim Walsh & Pat Forrest
Mammogram - linear calcification typical of DCIS


Detail of mammogram above - linear calcification in DCIS - Courtesy of Jim Walsh & Pat Forrest
Mammogram - linear calcification typical of DCIS



Intermediate grade DCIS and luminal microcalcs:


Intermediate grade DCIS & luminal calcs - specimen X ray showing two guide wires and scattered calcs
Intermediate grade DCIS and calcs - specimen x ray


Intermediate grade DCIS & luminal calcs
Intermediate grade DCIS and calcs

Intermediate grade DCIS and calcs Detail of luminal calc - intermediate grade DCIS


High grade DCIS & calcs




High grade DCIS & luminal calcs
High grade DCIS and calcs


High grade DCIS and calcs


Core biopsy - fragments of intracystic papillary carcinoma (in situ) with luminal calcs
Intracystic papillary carcinoma and calcs
Intracystic papillary carcinoma and calcs

Core biopsy - intracystic papillary carcinoma
- blue circle around shattered calc (left) and uniformly negative CK 5/6 (right)
Intracystic papillary carcinoma and calcs - low power Intracystic papillary carcinoma - CK 5/6 stain (negative)



LCIS



Florid LCIS & calcs



Florid LCIS & luminal calcs
Florid LCIS and calcs


Specimen X ray excision biopsy with localising needle - florid LCIS
Florid LCIS - specimen X ray


Florid LCIS - low power showing expansion of terminal ducts and lobules
Florid LCIS and calcs


Florid LCIS
"A" = terminal duct with Pagetoid subepithelial spread of LCIS cells (arrow)
"B" = area of acinar expansion ++ by LCIS cells
Florid LCIS and calcs


High power view of area of florid LCIS in lobules (left) and uniformly negative E cadherin (right)
Florid LCIS - high power LCIS - negative E cadherin immunostain


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