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Case of the month - September 2006



History - 50 year old female - clinical carcinoma left breast - core biopsies:



Low power view of core biopsies
Low power view of core biopsies - H&E


Medium power view of a core showing area of scarring
Medium power view of core biopsies showing area of scarring

High power view of core biopsies showing invasive carcinoma with grade 3 features
High power view of core biopsies showing invasive carcinoma with grade 3 features



Further views of core biopsies showing grade 3 features.
Note frequent mitoses on left and area of necrosis (A) in right hand image
Further high power view of core biopsy (H&E) Further high power view of core biopsy (H&E)


    Points to consider:

  • What are the main features in this biopsy?
  • What is your differential diagnosis?
  • What additional stains would you request?


Click for special stains



Click for discussion

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