HOME PAGE PRACTICE & PROTOCOLS INVESTIGATIONS BENIGN / BORDERLINE MALIGNANT CASE MATERIAL

Case of the month - August 2006
Special stains



History - 50 year old female - clinical carcinoma left breast - core biopsies:



PAS
PAS stain



PAS after diastase digestion
PAS stain after diastase digestion


CK pan
CK pan immunostain


ER (left) and S100 (right) - both negative
Immunostain for ER - negative Immunostain for S100 - negative


    Points to consider:

  • Note PAS +ve cytoplasmic granules partly resistant to diastase
  • Cytokeratin positive
  • ER and S100 negative


Click for discussion

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