The most visited pages in 2014
Click on images for linked pages

Intermediate grade DCIS - thumbnail Grading - thumbnail
Fibroadenoma - thumbail ADH - thumbnail



I am delighted to provide a link for the LORIS Trial which opened at the beginning of the year. The Trial compares surgery with surveillance for low risk DCIS.

The latest Image of the Quarter is an unusual lobular carcinoma variant which happens to show aberrant E Cadherin staining and, extremely unusually, absent beta catenin staining.

Colleagues have approached me to see if there was an appetite to publish brief case reports on this site. If there is enthusiasm I will set up a special section. If there is interest please contact me at this address:

The site is now over nine years old - it went live in February/March 2006. I am grateful to all the vistors, colleagues and trainees who help to encourage its further growth and development. Visitor numbers are steady at about 18,000 a month. The most frequently accessed pages remain broadly unchanged from previous years.

I am absolutely delighted to continue to work with colleagues on the Sloane Project. We have previously updated the ADH page on that site and I have used those images and text to update this site's Sloane Project ADH page in line with that. The Sloane Project is going from strength to strength. The steering group is immensely fortunate to have been guided by the expert chairmanship of Hugh Bishop succeeded two years ago by Professor Alastair Thompson with fantastic support from the NHS Breast Screening Programme. We are well advanced in consolidating our data and are about to publish some very interesting results on recurrences.

Last year we published in the European Journal of Cancer a very interesting study of adverse surgical outcomes in screen-detected DCIS having prevoiusly presented the paper at the European Breast Cancer Conference in Glasgow earlier that year. If you would like a pdf of the paper please get in touch via the following e mail address: '' .

Background, aims & optimum viewing:


An easily accessible entry point to the understanding of the pathology of breast diseases
Uses the flexibility of the web to allow rapid updating


Trainees in breast pathology
Teachers seeking educational material
The wider public


Cross-specialty topics such as immunohistochemistry and specimen handling protocols
Very richly illustrated with 'mouse-over' features on many illustrations
Extensive hyperlinking throughout site - easily navigable


Internet Explorer 5.0, Firefox 1.5 or Opera 9.0 or above
Screen resolution of 1280x800
Broadband internet connection


An evolving resource to cover all main areas of breast pathology
Developing links with other educational sites
Providing topical information
Developing interactive functionality


Dr Jeremy Thomas, Lead Consultant Pathologist, Edinburgh Breast Unit

Summary of topics covered on this site:


Specimen handling; BMS Trimming;
Reporting protocols; Communication;
Links to screening documents;


Immunohistochemistry; Genetics

Benign &

Epithelial proliferations - typical and atypical;
Fibroadenomas and related lesions;
Sclerosing lesions; Inflammations; Fibromatosis


Carcinoma in situ;
Common and uncommon cancers;
Grading and staging breast cancer;
Prognosis of breast cancer

It is emphasised that these pages are complementary to the many excellent texts and aids available to the student of breast pathology. The author recommends the following references as a starting point:

Site last updated 8/11/2015

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